BDBM197780 US9216986, 2-[(E)-2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-vinyl]-7-methoxy-quinoline

SMILES: COc1ccc2ccc(\C=C\c3nc4c(C)ncc(C)n4n3)nc2c1

InChI Key: InChIKey=IQHHSWDAHJQZSL-VQHVLOKHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PED10A (Homo sapiens (Human))	BDBM197780 (US9216986, 2-[(E)-2-(5,8-Dimethyl-[1,2,4]triazolo[...) Show SMILES COc1ccc2ccc(\C=C\c3nc4c(C)ncc(C)n4n3)nc2c1 Show InChI InChI=1S/C19H17N5O/c1-12-11-20-13(2)19-22-18(23-24(12)19)9-7-15-6-4-14-5-8-16(25-3)10-17(14)21-15/h4-11H,1-3H3/b9-7+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
					More data for this Ligand-Target Pair