BDBM197800 US9216988, 28

SMILES: CC(C)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1F)N1CCN(CC1)C(C)=O)C1CCC1

InChI Key: InChIKey=FTXMELYRXHLKSJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM197800 (US9216988, 28) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1F)N1CCN(CC1)C(C)=O)C1CCC1 Show InChI InChI=1S/C26H34FN3O3S/c1-19(2)21-8-11-25(12-9-21)34(32,33)30(23-5-4-6-23)18-22-7-10-24(17-26(22)27)29-15-13-28(14-16-29)20(3)31/h7-12,17,19,23H,4-6,13-16,18H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	n/a
Genentech, Inc. US Patent					Assay Description On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...				US Patent US9216988 (2015) BindingDB Entry DOI: 10.7270/Q2TB15QC
					More data for this Ligand-Target Pair