BDBM197849 US9216988, 112

SMILES: CC(=O)N1C[C@H]2C[C@@H]1CN2c1ccc(CN(CC(F)(F)F)S(=O)(=O)Cc2ccccc2)c(F)c1

InChI Key: InChIKey=VGXYYEYKMADKBQ-NHCUHLMSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM197849 (US9216988, 112) Show SMILES CC(=O)N1C[C@H]2C[C@@H]1CN2c1ccc(CN(CC(F)(F)F)S(=O)(=O)Cc2ccccc2)c(F)c1 |r| Show InChI InChI=1S/C23H25F4N3O3S/c1-16(31)29-12-21-9-20(29)13-30(21)19-8-7-18(22(24)10-19)11-28(15-23(25,26)27)34(32,33)14-17-5-3-2-4-6-17/h2-8,10,20-21H,9,11-15H2,1H3/t20-,21-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	7.4	n/a
Genentech, Inc. US Patent					Assay Description On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...				US Patent US9216988 (2015) BindingDB Entry DOI: 10.7270/Q2TB15QC
					More data for this Ligand-Target Pair