BDBM198011 US9221795, 7

SMILES: C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(C)c2c(=O)n1-c1cccnc1

InChI Key: InChIKey=SNRSHTHNVIZTLC-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM198011 (US9221795, 7) Show SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(C)c2c(=O)n1-c1cccnc1 |r| Show InChI InChI=1S/C21H19N9O/c1-11-5-3-7-15-16(11)20(31)30(13-6-4-8-25-10-13)19(27-15)12(2)26-18-14(9-22)17(23)28-21(24)29-18/h3-8,10,12H,1-2H3,(H5,23,24,26,28,29)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	n/a
Gilead Sciences, Inc. US Patent					Assay Description Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...				US Patent US9221795 (2015) BindingDB Entry DOI: 10.7270/Q29C6W8T
					More data for this Ligand-Target Pair