null
SMILES: Oc1ccc(CN2CC[C@@H](N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1
InChI Key: InChIKey=HEZHOLUAZMQEBN-OAQYLSRUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM198697 (US9221796, 25b) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.30 | -12.2 | n/a | n/a | n/a | n/a | n/a | n/a | 50 |
Bristol-Myers Squibb Company US Patent | Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo... | US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1 | |||||||||||
More data for this Ligand-Target Pair |