BDBM198844 US9221797, 7
SMILES: NC(=O)CCc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1
InChI Key: InChIKey=VMGGYSQUCLDMQG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FMS Substrate Peptide (aa 555-568) (Homo sapiens (Human)) | BDBM198844 (US9221797, 7) | GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS... | US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H | |||||||||||
More data for this Ligand-Target Pair |