BDBM198858 US9221797, 21

SMILES: COCCN(C)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key: InChIKey=JLYXGCSWHPWBKO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FMS Substrate Peptide (aa 555-568) (Homo sapiens (Human))	BDBM198858 (US9221797, 21) Show SMILES COCCN(C)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5O2/c1-25(2)11-9-18(10-12-25)21-15-19(26(3,4)31(5)13-14-33-6)7-8-22(21)30-24(32)23-28-17-20(16-27)29-23/h7-9,15,17H,10-14H2,1-6H3,(H,28,29)(H,30,32)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair
FMS Substrate Peptide (aa 555-568) (Homo sapiens (Human))	BDBM198858 (US9221797, 21) Show SMILES COCCN(C)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:27| Show InChI InChI=1S/C26H35N5O2/c1-25(2)11-9-18(10-12-25)21-15-19(26(3,4)31(5)13-14-33-6)7-8-22(21)30-24(32)23-28-17-20(16-27)29-23/h7-9,15,17H,10-14H2,1-6H3,(H,28,29)(H,30,32)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair