BDBM198892 US9221797, 77

SMILES: COCCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key: InChIKey=MWSYDGNFQSXUAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FMS Substrate Peptide (aa 555-568) (Homo sapiens (Human))	BDBM198892 (US9221797, 77) Show SMILES COCCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C29H40N6O2/c1-28(2)10-8-21(9-11-28)24-18-22(29(3,4)35-14-12-34(13-15-35)16-17-37-5)6-7-25(24)33-27(36)26-31-20-23(19-30)32-26/h6-8,18,20H,9-17H2,1-5H3,(H,31,32)(H,33,36)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
					More data for this Ligand-Target Pair