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SMILES: CC1(C)CCC(=CC1)c1cc(CN2CCN(CCO)CC2)ccc1NC(=O)c1nc(c[nH]1)C#N

InChI Key: InChIKey=ZRBHOXZJRFQVDF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198907   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor [555-568]


(Homo sapiens (Human))		BDBM198907
PNG
(US9221797, 150)
Show SMILES CC1(C)CCC(=CC1)c1cc(CN2CCN(CCO)CC2)ccc1NC(=O)c1nc(c[nH]1)C#N |c:5|
Show InChI InChI=1S/C26H34N6O2/c1-26(2)7-5-20(6-8-26)22-15-19(18-32-11-9-31(10-12-32)13-14-33)3-4-23(22)30-25(34)24-28-17-21(16-27)29-24/h3-5,15,17,33H,6-14,18H2,1-2H3,(H,28,29)(H,30,34)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.75n/an/an/an/a7.5n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...

US Patent US9221797 (2015)


BindingDB Entry DOI: 10.7270/Q2W37V4H
More data for this
Ligand-Target Pair