BDBM198970 BDBM199009::BDBM199010::US9221832, 34

SMILES: FC(F)(F)c1cccc(CC(=O)NC2COc3ncccc23)c1Cl

InChI Key: InChIKey=NOLLGHUYWWIUQZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 198970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM198970 (BDBM199009 | BDBM199010 | US9221832, 34) Show SMILES FC(F)(F)c1cccc(CC(=O)NC2COc3ncccc23)c1Cl Show InChI InChI=1S/C16H12ClF3N2O2/c17-14-9(3-1-5-11(14)16(18,19)20)7-13(23)22-12-8-24-15-10(12)4-2-6-21-15/h1-6,12H,7-8H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whol...				US Patent US9221832 (2015) BindingDB Entry DOI: 10.7270/Q2C53JPG
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM198970 (BDBM199009 | BDBM199010 | US9221832, 34) Show SMILES FC(F)(F)c1cccc(CC(=O)NC2COc3ncccc23)c1Cl Show InChI InChI=1S/C16H12ClF3N2O2/c17-14-9(3-1-5-11(14)16(18,19)20)7-13(23)22-12-8-24-15-10(12)4-2-6-21-15/h1-6,12H,7-8H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whol...				US Patent US9221832 (2015) BindingDB Entry DOI: 10.7270/Q2C53JPG
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM198970 (BDBM199009 | BDBM199010 | US9221832, 34) Show SMILES FC(F)(F)c1cccc(CC(=O)NC2COc3ncccc23)c1Cl Show InChI InChI=1S/C16H12ClF3N2O2/c17-14-9(3-1-5-11(14)16(18,19)20)7-13(23)22-12-8-24-15-10(12)4-2-6-21-15/h1-6,12H,7-8H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whol...				US Patent US9221832 (2015) BindingDB Entry DOI: 10.7270/Q2C53JPG
					More data for this Ligand-Target Pair