BDBM199123 N-(4-(1-(4,6-bis((4-hydroxyphenyl)amino)-1,3,5-triazin-2-yl)-5-(4-methoxyphenyl)-1H-pyrazol-3-yl)phenyl)-4-methylbenzenesulphonamide (8e)

SMILES: COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccc(O)cc2)nc(Nc2ccc(O)cc2)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

InChI Key: InChIKey=NNXCDSUUJQMFBA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (MMP-9) (Rattus norvegicus (Rat))	BDBM199123 (N-(4-(1-(4,6-bis((4-hydroxyphenyl)amino)-1,3,5-tri...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccc(O)cc2)nc(Nc2ccc(O)cc2)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C38H32N8O5S/c1-24-3-21-33(22-4-24)52-51-50-45-29-9-5-25(6-10-29)34-23-35(26-7-19-32(49-2)20-8-26)46(44-34)38-42-36(39-27-11-15-30(47)16-12-27)41-37(43-38)40-28-13-17-31(48)18-14-28/h3-23,45,47-48H,1-2H3,(H2,39,40,41,42,43)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.34	n/a	n/a	n/a	n/a	7.5	25
Zhejiang Hospital					Assay Description where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...				Chem Biol Drug Des 88: 756-765 (2016) Article DOI: 10.1111/cbdd.12807 BindingDB Entry DOI: 10.7270/Q2ZW1JR4
					More data for this Ligand-Target Pair
Matrix metalloproteinase-2 (MMP-2) (Rattus norvegicus (Rat))	BDBM199123 (N-(4-(1-(4,6-bis((4-hydroxyphenyl)amino)-1,3,5-tri...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccc(O)cc2)nc(Nc2ccc(O)cc2)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C38H32N8O5S/c1-24-3-21-33(22-4-24)52-51-50-45-29-9-5-25(6-10-29)34-23-35(26-7-19-32(49-2)20-8-26)46(44-34)38-42-36(39-27-11-15-30(47)16-12-27)41-37(43-38)40-28-13-17-31(48)18-14-28/h3-23,45,47-48H,1-2H3,(H2,39,40,41,42,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.12	n/a	n/a	n/a	n/a	7.5	25
Zhejiang Hospital					Assay Description where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...				Chem Biol Drug Des 88: 756-765 (2016) Article DOI: 10.1111/cbdd.12807 BindingDB Entry DOI: 10.7270/Q2ZW1JR4
					More data for this Ligand-Target Pair