BDBM199125 N-(4-(1-(4,6-bis(o-tolylamino)-1,3,5-triazin-2-yl)-5-(4-methoxyphenyl)-1H-pyrazol-3-yl)phenyl)-4-methylbenzenesulphonamide (8g)

SMILES: COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccccc2C)nc(Nc2ccccc2C)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

InChI Key: InChIKey=HBFSVAVZJFTMSI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (MMP-9) (Rattus norvegicus (Rat))	BDBM199125 (N-(4-(1-(4,6-bis(o-tolylamino)-1,3,5-triazin-2-yl)...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccccc2C)nc(Nc2ccccc2C)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C40H36N8O3S/c1-26-13-23-33(24-14-26)52-51-50-47-31-19-15-29(16-20-31)36-25-37(30-17-21-32(49-4)22-18-30)48(46-36)40-44-38(41-34-11-7-5-9-27(34)2)43-39(45-40)42-35-12-8-6-10-28(35)3/h5-25,47H,1-4H3,(H2,41,42,43,44,45)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58.2	n/a	n/a	n/a	n/a	7.5	25
Zhejiang Hospital					Assay Description where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...				Chem Biol Drug Des 88: 756-765 (2016) Article DOI: 10.1111/cbdd.12807 BindingDB Entry DOI: 10.7270/Q2ZW1JR4
					More data for this Ligand-Target Pair
Matrix metalloproteinase-2 (MMP-2) (Rattus norvegicus (Rat))	BDBM199125 (N-(4-(1-(4,6-bis(o-tolylamino)-1,3,5-triazin-2-yl)...) Show SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccccc2C)nc(Nc2ccccc2C)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 Show InChI InChI=1S/C40H36N8O3S/c1-26-13-23-33(24-14-26)52-51-50-47-31-19-15-29(16-20-31)36-25-37(30-17-21-32(49-4)22-18-30)48(46-36)40-44-38(41-34-11-7-5-9-27(34)2)43-39(45-40)42-35-12-8-6-10-28(35)3/h5-25,47H,1-4H3,(H2,41,42,43,44,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67.1	n/a	n/a	n/a	n/a	7.5	25
Zhejiang Hospital					Assay Description where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...				Chem Biol Drug Des 88: 756-765 (2016) Article DOI: 10.1111/cbdd.12807 BindingDB Entry DOI: 10.7270/Q2ZW1JR4
					More data for this Ligand-Target Pair