null

SMILES: COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4OC

InChI Key: InChIKey=MULALUUHQOTCGR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 199157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM199157 (3,10,11-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4...) Show SMILES COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4OC Show InChI InChI=1S/C21H25NO4/c1-24-19-5-4-13-10-17-16-12-18(23)20(25-2)11-14(16)6-8-22(17)9-7-15(13)21(19)26-3/h4-5,11-12,17,23H,6-10H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University					Assay Description The transfection of plasmid and membrane preparations was conducted as described in our previous report, with 0.7 nm [3H] SCH23390 (D1R) or [3H]Spipe...				Chem Biol Drug Des 88: 599-607 (2016) Article DOI: 10.1111/cbdd.12796 BindingDB Entry DOI: 10.7270/Q2QF8RQ5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM199157 (3,10,11-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4...) Show SMILES COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4OC Show InChI InChI=1S/C21H25NO4/c1-24-19-5-4-13-10-17-16-12-18(23)20(25-2)11-14(16)6-8-22(17)9-7-15(13)21(19)26-3/h4-5,11-12,17,23H,6-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	84.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University					Assay Description The transfection of plasmid and membrane preparations was conducted as described in our previous report, with 0.7 nm [3H] SCH23390 (D1R) or [3H]Spipe...				Chem Biol Drug Des 88: 599-607 (2016) Article DOI: 10.1111/cbdd.12796 BindingDB Entry DOI: 10.7270/Q2QF8RQ5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM199157 (3,10,11-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4...) Show SMILES COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4OC Show InChI InChI=1S/C21H25NO4/c1-24-19-5-4-13-10-17-16-12-18(23)20(25-2)11-14(16)6-8-22(17)9-7-15(13)21(19)26-3/h4-5,11-12,17,23H,6-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	284	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University					Assay Description The transfection of plasmid and membrane preparations was conducted as described in our previous report, with 0.7 nm [3H] SCH23390 (D1R) or [3H]Spipe...				Chem Biol Drug Des 88: 599-607 (2016) Article DOI: 10.1111/cbdd.12796 BindingDB Entry DOI: 10.7270/Q2QF8RQ5
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM199157 (3,10,11-trimethoxy-5,6,8,9,14,14a-hexahydrobenzo[4...) Show SMILES COc1cc2CCN3CCc4c(CC3c2cc1O)ccc(OC)c4OC Show InChI InChI=1S/C21H25NO4/c1-24-19-5-4-13-10-17-16-12-18(23)20(25-2)11-14(16)6-8-22(17)9-7-15(13)21(19)26-3/h4-5,11-12,17,23H,6-10H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	7.5	n/a
Fudan University					Assay Description The [35S]GTPγS binding assay was performed at 30 °C for 30 min containing 10 μgof membrane protein in a final volume of 100 μL with va...				Chem Biol Drug Des 88: 599-607 (2016) Article DOI: 10.1111/cbdd.12796 BindingDB Entry DOI: 10.7270/Q2QF8RQ5
					More data for this Ligand-Target Pair