BDBM199184 N-(3-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-amine (8c)

SMILES: COc1cccc(CNc2c3CCCCc3nc3ccccc23)c1

InChI Key: InChIKey=QOASWZIFVOPOIY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM199184 (N-(3-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...) Show SMILES COc1cccc(CNc2c3CCCCc3nc3ccccc23)c1 Show InChI InChI=1S/C21H22N2O/c1-24-16-8-6-7-15(13-16)14-22-21-17-9-2-4-11-19(17)23-20-12-5-3-10-18(20)21/h2,4,6-9,11,13H,3,5,10,12,14H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	8.0	25
University of Waterloo					Assay Description Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...				Chem Biol Drug Des 88: 710-723 (2016) Article DOI: 10.1111/cbdd.12800 BindingDB Entry DOI: 10.7270/Q26D5RSX
					More data for this Ligand-Target Pair
Cholinesterases (Homo sapiens (Human))	BDBM199184 (N-(3-Methoxybenzyl)-1,2,3,4-tetrahydroacridin-9-am...) Show SMILES COc1cccc(CNc2c3CCCCc3nc3ccccc23)c1 Show InChI InChI=1S/C21H22N2O/c1-24-16-8-6-7-15(13-16)14-22-21-17-9-2-4-11-19(17)23-20-12-5-3-10-18(20)21/h2,4,6-9,11,13H,3,5,10,12,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	25
University of Waterloo					Assay Description Test compounds were prepared in DMSO (maximum concentration used 1% v/v), and 10 μL of each (0.001-25 μm final concentration range) was inc...				Chem Biol Drug Des 88: 710-723 (2016) Article DOI: 10.1111/cbdd.12800 BindingDB Entry DOI: 10.7270/Q26D5RSX
					More data for this Ligand-Target Pair