BDBM19921 3-arylquinazolinone, 1al::5,7-dihydroxy-3-(6-hydroxypyridin-3-yl)-3,4-dihydroquinazolin-4-one

SMILES: Oc1cc(O)c2c(c1)ncn(-c1ccc(=O)[nH]c1)c2=O

InChI Key: InChIKey=XKFWSLXLSOZPJJ-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM19921 (3-arylquinazolinone, 1al | 5,7-dihydroxy-3-(6-hydr...) Show SMILES Oc1cc(O)c2c(c1)ncn(-c1ccc(=O)[nH]c1)c2=O Show InChI InChI=1S/C13H9N3O4/c17-8-3-9-12(10(18)4-8)13(20)16(6-15-9)7-1-2-11(19)14-5-7/h1-6,17-18H,(H,14,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.17E+4	n/a	9.76E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19921 (3-arylquinazolinone, 1al | 5,7-dihydroxy-3-(6-hydr...) Show SMILES Oc1cc(O)c2c(c1)ncn(-c1ccc(=O)[nH]c1)c2=O Show InChI InChI=1S/C13H9N3O4/c17-8-3-9-12(10(18)4-8)13(20)16(6-15-9)7-1-2-11(19)14-5-7/h1-6,17-18H,(H,14,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.69E+4	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair