BDBM19951 3-arylquinazolinone, 1aar::7-hydroxy-5-(hydroxymethyl)-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one

SMILES: OCc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12

InChI Key: InChIKey=ZPKUQXYUNFFPKO-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM19951 (3-arylquinazolinone, 1aar | 7-hydroxy-5-(hydroxyme...) Show SMILES OCc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 Show InChI InChI=1S/C15H12N2O4/c18-7-9-5-12(20)6-13-14(9)15(21)17(8-16-13)10-1-3-11(19)4-2-10/h1-6,8,18-20H,7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	4.46E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19951 (3-arylquinazolinone, 1aar | 7-hydroxy-5-(hydroxyme...) Show SMILES OCc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 Show InChI InChI=1S/C15H12N2O4/c18-7-9-5-12(20)6-13-14(9)15(21)17(8-16-13)10-1-3-11(19)4-2-10/h1-6,8,18-20H,7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair