BDBM199988 US9227959, 2
SMILES: Clc1cccc(c1)C#Cc1ccc(nc1)C(=O)N1CCOCC1
InChI Key: InChIKey=LBLXFRRQZJVWJO-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 5a (mGluR5) (Homo sapiens (Human)) | BDBM199988 (US9227959, 2) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 19 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Hoffman-La Roche Inc. US Patent | Assay Description For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ... | US Patent US9227959 (2016) BindingDB Entry DOI: 10.7270/Q25D8QNJ | |||||||||||
More data for this Ligand-Target Pair |