BDBM20044 5-chloro-6-hydrazinyl-1,3-diazinane-2,4-dione::uracil, 14
SMILES: NNc1[nH]c(=O)[nH]c(=O)c1Cl
InChI Key: InChIKey=CEFVVOSTKQAVJQ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidine Phosphorylase (TP) (Escherichia coli) | BDBM20044 (5-chloro-6-hydrazinyl-1,3-diazinane-2,4-dione | ur...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic | Assay Description The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b... | Bioorg Med Chem Lett 16: 1335-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.050 BindingDB Entry DOI: 10.7270/Q2QR4VCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidine Phosphorylase (TP) (Homo sapiens (Human)) | BDBM20044 (5-chloro-6-hydrazinyl-1,3-diazinane-2,4-dione | ur...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | 6.4 | 37 |
Academy of Sciences of the Czech Republic | Assay Description The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b... | Bioorg Med Chem Lett 16: 1335-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.050 BindingDB Entry DOI: 10.7270/Q2QR4VCH | |||||||||||
More data for this Ligand-Target Pair |