BDBM200613 US10590139, Example 39::US9227975, 39::US9795611, 39

SMILES: C[C@H]1CN(CCN1)C(=O)Nc1cnc2ccc(nn12)N1CCC[C@@H]1c1cc(F)ccc1F

InChI Key: InChIKey=VWCONLJBMSCZJJ-KBXCAEBGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 200613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200613 (US10590139, Example 39 | US9227975, 39 | US9795611...) Show SMILES C[C@H]1CN(CCN1)C(=O)Nc1cnc2ccc(nn12)N1CCC[C@@H]1c1cc(F)ccc1F |r| Show InChI InChI=1S/C22H25F2N7O/c1-14-13-29(10-8-25-14)22(32)27-21-12-26-19-6-7-20(28-31(19)21)30-9-2-3-18(30)16-11-15(23)4-5-17(16)24/h4-7,11-12,14,18,25H,2-3,8-10,13H2,1H3,(H,27,32)/t14-,18+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.9	n/a	n/a	n/a	n/a	7.5	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9227975 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WKV
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200613 (US10590139, Example 39 | US9227975, 39 | US9795611...) Show SMILES C[C@H]1CN(CCN1)C(=O)Nc1cnc2ccc(nn12)N1CCC[C@@H]1c1cc(F)ccc1F |r| Show InChI InChI=1S/C22H25F2N7O/c1-14-13-29(10-8-25-14)22(32)27-21-12-26-19-6-7-20(28-31(19)21)30-9-2-3-18(30)16-11-15(23)4-5-17(16)24/h4-7,11-12,14,18,25H,2-3,8-10,13H2,1H3,(H,27,32)/t14-,18+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.9	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US10590139 (2020)
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM200613 (US10590139, Example 39 | US9227975, 39 | US9795611...) Show SMILES C[C@H]1CN(CCN1)C(=O)Nc1cnc2ccc(nn12)N1CCC[C@@H]1c1cc(F)ccc1F |r| Show InChI InChI=1S/C22H25F2N7O/c1-14-13-29(10-8-25-14)22(32)27-21-12-26-19-6-7-20(28-31(19)21)30-9-2-3-18(30)16-11-15(23)4-5-17(16)24/h4-7,11-12,14,18,25H,2-3,8-10,13H2,1H3,(H,27,32)/t14-,18+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.9	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9795611 (2017) BindingDB Entry DOI: 10.7270/Q25T3NMH
					More data for this Ligand-Target Pair