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SMILES: FC(F)(F)c1cccc(CN2c3scnc3SCC2=O)c1

InChI Key: InChIKey=AHUVYFCRZMZCPE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200933   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))		BDBM200933
PNG
(US9533999, ii-2)
Show SMILES FC(F)(F)c1cccc(CN2c3scnc3SCC2=O)c1
Show InChI InChI=1S/C13H9F3N2OS2/c14-13(15,16)9-3-1-2-8(4-9)5-18-10(19)6-20-11-12(18)21-7-17-11/h1-4,7H,5-6H2
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US Patent
n/an/a 320n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...

US Patent US9533999 (2017)


BindingDB Entry DOI: 10.7270/Q21V5C4S
More data for this
Ligand-Target Pair