BDBM201015 US9540373, 4::US9879026, Example 4::USRE47636, Example 4

SMILES: CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1

InChI Key: InChIKey=CXEHWKQDWKZLQY-MSZDEVHKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 201015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair