BDBM201074 US9233953, 35

SMILES: Fc1ccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2ccc(cn2)C(F)(F)F)c(F)c1

InChI Key: InChIKey=BZKDQFDZADCMRZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM201074 (US9233953, 35) Show SMILES Fc1ccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2ccc(cn2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C22H22F5N3O3S/c23-16-2-3-17(18(24)11-16)19-13-29(20-4-1-15(12-28-20)22(25,26)27)7-8-30(19)21(31)14-5-9-34(32,33)10-6-14/h1-4,11-12,14,19H,5-10,13H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...				US Patent US9233953 (2016) BindingDB Entry DOI: 10.7270/Q2Q81BVM
					More data for this Ligand-Target Pair