BDBM201164 US9233953, 124

SMILES: COc1ccc(cc1C(F)(F)F)N1CCN(C(C1)c1ccccc1)C(=O)C1CCS(=O)(=O)CC1

InChI Key: InChIKey=NJFOJGLBXVPYNX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM201164 (US9233953, 124) Show SMILES COc1ccc(cc1C(F)(F)F)N1CCN(C(C1)c1ccccc1)C(=O)C1CCS(=O)(=O)CC1 Show InChI InChI=1S/C24H27F3N2O4S/c1-33-22-8-7-19(15-20(22)24(25,26)27)28-11-12-29(21(16-28)17-5-3-2-4-6-17)23(30)18-9-13-34(31,32)14-10-18/h2-8,15,18,21H,9-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...				US Patent US9233953 (2016) BindingDB Entry DOI: 10.7270/Q2Q81BVM
					More data for this Ligand-Target Pair