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SMILES: COc1ccc(CN(CCCOc2cccc(CC(N)=O)c2)CC(c2ccccc2)c2ccccc2)cc1F

InChI Key: InChIKey=OPWHNQJROOXYEZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20169   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM20169
PNG
(2-(3-{3-[(2,2-diphenylethyl)[(3-fluoro-4-methoxyph...)
Show SMILES COc1ccc(CN(CCCOc2cccc(CC(N)=O)c2)CC(c2ccccc2)c2ccccc2)cc1F
Show InChI InChI=1S/C33H35FN2O3/c1-38-32-17-16-26(21-31(32)34)23-36(18-9-19-39-29-15-8-10-25(20-29)22-33(35)37)24-30(27-11-4-2-5-12-27)28-13-6-3-7-14-28/h2-8,10-17,20-21,30H,9,18-19,22-24H2,1H3,(H2,35,37)
PDB

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antibodypedia
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UniChem

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Similars
Article
PubMed
n/an/an/an/a 250n/an/a7.522



GlaxoSmithKline



Assay Description
The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...

J Med Chem 45: 1963-6 (2002)


Article DOI: 10.1021/jm0255116
BindingDB Entry DOI: 10.7270/Q2319T5G
More data for this
Ligand-Target Pair