BDBM202282 US9238619, 36

SMILES: Cn1cc(cn1)S(=O)(=O)NCCOc1cccc(c1)C(CN1CCC1)Cc1ccccc1

InChI Key: InChIKey=TYSSRHFFJQXYGK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM202282 (US9238619, 36) Show SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1cccc(c1)C(CN1CCC1)Cc1ccccc1 Show InChI InChI=1S/C24H30N4O3S/c1-27-19-24(17-25-27)32(29,30)26-11-14-31-23-10-5-9-21(16-23)22(18-28-12-6-13-28)15-20-7-3-2-4-8-20/h2-5,7-10,16-17,19,22,26H,6,11-15,18H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F
					More data for this Ligand-Target Pair