BDBM202349 US9238619, 68

SMILES: O=S(=O)(CC1CC1)NCc1cccc(c1)C1(Cc2ccccc2)CCNC1

InChI Key: InChIKey=LPVHWPGGFBBWCR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM202349 (US9238619, 68) Show SMILES O=S(=O)(CC1CC1)NCc1cccc(c1)C1(Cc2ccccc2)CCNC1 Show InChI InChI=1S/C22H28N2O2S/c25-27(26,16-19-9-10-19)24-15-20-7-4-8-21(13-20)22(11-12-23-17-22)14-18-5-2-1-3-6-18/h1-8,13,19,23-24H,9-12,14-17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F
					More data for this Ligand-Target Pair