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BDBM202349 US9238619, 68

SMILES: O=S(=O)(CC1CC1)NCc1cccc(c1)C1(Cc2ccccc2)CCNC1

InChI Key: InChIKey=LPVHWPGGFBBWCR-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202349   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202349
PNG
(US9238619, 68)
Show SMILES O=S(=O)(CC1CC1)NCc1cccc(c1)C1(Cc2ccccc2)CCNC1
Show InChI InChI=1/C22H28N2O2S/c25-27(26,16-19-9-10-19)24-15-20-7-4-8-21(13-20)22(11-12-23-17-22)14-18-5-2-1-3-6-18/h1-8,13,19,23-24H,9-12,14-17H2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair