BDBM202352 US9238619, 71
SMILES: Cn1cnc(c1)S(=O)(=O)NCCOc1cccc(c1)C1(Cc2ccccc2)CCN(C1)C(=O)C(F)F
InChI Key: InChIKey=OBDPJNWADSEKSU-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202352 (US9238619, 71) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair |