BDBM20323 3-[(4-tert-butylphenyl)methyl]-1-[(1R)-1-(3-fluoro-4-methanesulfonamidophenyl)ethyl]thiourea::thiourea analogue, 18
SMILES: C[C@@H](NC(=S)NCc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1
InChI Key: InChIKey=DEJBDWNJCXYNAW-CQSZACIVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Vanilloid receptor (Rattus norvegicus (rat)) | BDBM20323 (3-[(4-tert-butylphenyl)methyl]-1-[(1R)-1-(3-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 39.2 | -10.5 | n/a | n/a | 37 | n/a | n/a | 7.4 | 37 |
Seoul National University | Assay Description Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b... | Bioorg Med Chem 15: 6043-53 (2007) Article DOI: 10.1016/j.bmc.2007.06.041 BindingDB Entry DOI: 10.7270/Q2X928KS | |||||||||||
More data for this Ligand-Target Pair |