BDBM203293 US10227340, Example 59::US9242975, 59

SMILES: CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1nc(cs1)C(=O)NCC1CCCO1

InChI Key: InChIKey=WDMDFWHUDRRESW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM203293 (US10227340, Example 59 | US9242975, 59) Show SMILES CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1nc(cs1)C(=O)NCC1CCCO1 Show InChI InChI=1S/C24H26N6O2S2/c1-14(2)28-19-9-22(29-15-5-6-18-21(8-15)34-13-27-18)25-11-17(19)24-30-20(12-33-24)23(31)26-10-16-4-3-7-32-16/h5-6,8-9,11-14,16H,3-4,7,10H2,1-2H3,(H,26,31)(H2,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...				J Med Chem 51: 1719-29 (2008) BindingDB Entry DOI: 10.7270/Q29C70Q8
					More data for this Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM203293 (US10227340, Example 59 | US9242975, 59) Show SMILES CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1nc(cs1)C(=O)NCC1CCCO1 Show InChI InChI=1S/C24H26N6O2S2/c1-14(2)28-19-9-22(29-15-5-6-18-21(8-15)34-13-27-18)25-11-17(19)24-30-20(12-33-24)23(31)26-10-16-4-3-7-32-16/h5-6,8-9,11-14,16H,3-4,7,10H2,1-2H3,(H,26,31)(H2,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.2	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substrates...				US Patent US9242975 (2016) BindingDB Entry DOI: 10.7270/Q2MC8XVD
					More data for this Ligand-Target Pair