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SMILES: FC(F)(F)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)ccc1N1CCCCCC1

InChI Key: InChIKey=HROAXNCXUIKFGJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20358   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20358
PNG
(1-{[4-(azepan-1-yl)-3-(trifluoromethyl)phenyl]meth...)
Show SMILES FC(F)(F)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)ccc1N1CCCCCC1
Show InChI InChI=1S/C22H24F3N5O/c23-22(24,25)17-12-15(8-9-20(17)30-10-3-1-2-4-11-30)13-26-21(31)28-18-6-5-7-19-16(18)14-27-29-19/h5-9,12,14H,1-4,10-11,13H2,(H,27,29)(H2,26,28,31)
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Similars
Article
PubMed
n/an/an/an/a 29.5n/an/a7.422



Abbott Laboratories



Assay Description
The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...

J Med Chem 50: 3651-60 (2007)


Article DOI: 10.1021/jm070276i
BindingDB Entry DOI: 10.7270/Q2SJ1HWH
More data for this
Ligand-Target Pair