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SMILES: O=C(NCc1ccc(cc1Cc1ccccc1)N1[C@H]2CC[C@@H]1CCC2)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=NNLLVESVSSYGMW-PSWAGMNNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20379   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20379
PNG
(1-(2-Benzyl-4-(8-azabicyclo[3.2.1]octan-8-yl)benzy...)
Show SMILES O=C(NCc1ccc(cc1Cc1ccccc1)N1[C@H]2CC[C@@H]1CCC2)Nc1cccc2[nH]ncc12 |r,THB:7:17:23.22.24:19.20|
Show InChI InChI=1S/C29H31N5O/c35-29(32-27-10-5-11-28-26(27)19-31-33-28)30-18-21-12-13-25(34-23-8-4-9-24(34)15-14-23)17-22(21)16-20-6-2-1-3-7-20/h1-3,5-7,10-13,17,19,23-24H,4,8-9,14-16,18H2,(H,31,33)(H2,30,32,35)/t23-,24+
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Article
PubMed
n/an/an/an/a 22.4n/an/an/an/a



Abbott Laboratories



Assay Description
The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...

J Med Chem 50: 3651-60 (2007)


Article DOI: 10.1021/jm070276i
BindingDB Entry DOI: 10.7270/Q2SJ1HWH
More data for this
Ligand-Target Pair