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SMILES: CC(NC(=O)Nc1cccc2[nH]ncc12)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SLVGTOOOMMCFEW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20403   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20403
PNG
(3-1H-indazol-4-yl-1-{1-[4-(trifluoromethyl)phenyl]...)
Show SMILES CC(NC(=O)Nc1cccc2[nH]ncc12)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C17H15F3N4O/c1-10(11-5-7-12(8-6-11)17(18,19)20)22-16(25)23-14-3-2-4-15-13(14)9-21-24-15/h2-10H,1H3,(H,21,24)(H2,22,23,25)
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Article
PubMed
n/an/an/an/a 47n/an/a7.422



Abbott Laboratories



Assay Description
The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...

Bioorg Med Chem Lett 17: 3894-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.105
BindingDB Entry DOI: 10.7270/Q2NV9GH2
More data for this
Ligand-Target Pair