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SMILES: Fc1cc(CNC(=O)Nc2cccc3[nH]ccc23)ccc1C(F)(F)F

InChI Key: InChIKey=AGCHCFDXRNRRRU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20442   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20442
PNG
(1-{[3-fluoro-4-(trifluoromethyl)phenyl]methyl}-3-1...)
Show SMILES Fc1cc(CNC(=O)Nc2cccc3[nH]ccc23)ccc1C(F)(F)F
Show InChI InChI=1S/C17H13F4N3O/c18-13-8-10(4-5-12(13)17(19,20)21)9-23-16(25)24-15-3-1-2-14-11(15)6-7-22-14/h1-8,22H,9H2,(H2,23,24,25)
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Similars
Article
PubMed
n/an/an/an/a 40n/an/a7.422



Abbott Laboratories



Assay Description
The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...

Bioorg Med Chem 14: 4740-9 (2006)


Article DOI: 10.1016/j.bmc.2006.03.027
BindingDB Entry DOI: 10.7270/Q2DB8035
More data for this
Ligand-Target Pair