null

SMILES: CC(C)(C)c1ccc(cc1)-c1cncc(Nc2ccc3OCCOc3c2)c1

InChI Key: InChIKey=BEASIIHSNRSTND-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20515 (5-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...) Show SMILES CC(C)(C)c1ccc(cc1)-c1cncc(Nc2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C23H24N2O2/c1-23(2,3)18-6-4-16(5-7-18)17-12-20(15-24-14-17)25-19-8-9-21-22(13-19)27-11-10-26-21/h4-9,12-15,25H,10-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3497-514 (2007) Article DOI: 10.1021/jm070189q BindingDB Entry DOI: 10.7270/Q2W957GV
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20515 (5-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...) Show SMILES CC(C)(C)c1ccc(cc1)-c1cncc(Nc2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C23H24N2O2/c1-23(2,3)18-6-4-16(5-7-18)17-12-20(15-24-14-17)25-19-8-9-21-22(13-19)27-11-10-26-21/h4-9,12-15,25H,10-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	7.4	22
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3497-514 (2007) Article DOI: 10.1021/jm070189q BindingDB Entry DOI: 10.7270/Q2W957GV
					More data for this Ligand-Target Pair