null

SMILES: CC(C)(C)c1ccc(cc1)-c1ccnc(Nc2ccc3OCCOc3c2)n1

InChI Key: InChIKey=CCSHHOSWJAFQQA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20519 (4-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...) Show SMILES CC(C)(C)c1ccc(cc1)-c1ccnc(Nc2ccc3OCCOc3c2)n1 Show InChI InChI=1S/C22H23N3O2/c1-22(2,3)16-6-4-15(5-7-16)18-10-11-23-21(25-18)24-17-8-9-19-20(14-17)27-13-12-26-19/h4-11,14H,12-13H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3497-514 (2007) Article DOI: 10.1021/jm070189q BindingDB Entry DOI: 10.7270/Q2W957GV
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20519 (4-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...) Show SMILES CC(C)(C)c1ccc(cc1)-c1ccnc(Nc2ccc3OCCOc3c2)n1 Show InChI InChI=1S/C22H23N3O2/c1-22(2,3)16-6-4-15(5-7-16)18-10-11-23-21(25-18)24-17-8-9-19-20(14-17)27-13-12-26-19/h4-11,14H,12-13H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	7.4	22
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3497-514 (2007) Article DOI: 10.1021/jm070189q BindingDB Entry DOI: 10.7270/Q2W957GV
					More data for this Ligand-Target Pair