null

SMILES: CN(c1ccc2OCCOc2c1)c1cc(ncn1)-c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=MVDVGIXKGPAUIJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20525 (6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...) Show SMILES CN(c1ccc2OCCOc2c1)c1cc(ncn1)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C23H25N3O2/c1-23(2,3)17-7-5-16(6-8-17)19-14-22(25-15-24-19)26(4)18-9-10-20-21(13-18)28-12-11-27-20/h5-10,13-15H,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3497-514 (2007) Article DOI: 10.1021/jm070189q BindingDB Entry DOI: 10.7270/Q2W957GV
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20525 (6-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodio...) Show SMILES CN(c1ccc2OCCOc2c1)c1cc(ncn1)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C23H25N3O2/c1-23(2,3)17-7-5-16(6-8-17)19-14-22(25-15-24-19)26(4)18-9-10-20-21(13-18)28-12-11-27-20/h5-10,13-15H,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	7.4	22
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3497-514 (2007) Article DOI: 10.1021/jm070189q BindingDB Entry DOI: 10.7270/Q2W957GV
					More data for this Ligand-Target Pair