BDBM205410 US9249151, 56

SMILES: CC(N)C(=O)Nc1cc(Cl)cc(NC(=O)c2ccccn2)n1

InChI Key: InChIKey=ZCWCDZGQFPATQN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of apoptosis protein 1 (IAP1) (Homo sapiens (Human))	BDBM205410 (US9249151, 56) Show SMILES CC(N)C(=O)Nc1cc(Cl)cc(NC(=O)c2ccccn2)n1 Show InChI InChI=1S/C14H14ClN5O2/c1-8(16)13(21)19-11-6-9(15)7-12(18-11)20-14(22)10-4-2-3-5-17-10/h2-8H,16H2,1H3,(H2,18,19,20,21,22)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...				US Patent US9249151 (2016) BindingDB Entry DOI: 10.7270/Q24748P2
					More data for this Ligand-Target Pair
X-linked inhibitor of apoptosis protein BIR3 domain (XIAP BIR-3) (Homo sapiens (Human))	BDBM205410 (US9249151, 56) Show SMILES CC(N)C(=O)Nc1cc(Cl)cc(NC(=O)c2ccccn2)n1 Show InChI InChI=1S/C14H14ClN5O2/c1-8(16)13(21)19-11-6-9(15)7-12(18-11)20-14(22)10-4-2-3-5-17-10/h2-8H,16H2,1H3,(H2,18,19,20,21,22)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...				US Patent US9249151 (2016) BindingDB Entry DOI: 10.7270/Q24748P2
					More data for this Ligand-Target Pair