BDBM205715 US9255090, 184

SMILES: COc1cc(CC(O)=O)ccc1-c1ccc(F)c2CCN(Cc12)C(=O)[C@@H]1C[C@H]1c1ccccc1

InChI Key: InChIKey=PJDJLXTZYRHZRB-XZOQPEGZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM205715 (US9255090, 184) Show SMILES COc1cc(CC(O)=O)ccc1-c1ccc(F)c2CCN(Cc12)C(=O)[C@@H]1C[C@H]1c1ccccc1 Show InChI InChI=1S/C28H26FNO4/c1-34-26-13-17(14-27(31)32)7-8-21(26)19-9-10-25(29)20-11-12-30(16-24(19)20)28(33)23-15-22(23)18-5-3-2-4-6-18/h2-10,13,22-23H,11-12,14-16H2,1H3,(H,31,32)/t22-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.0	25
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...				US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2
					More data for this Ligand-Target Pair