BDBM205965 US9255090, 434

SMILES: CCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)NCc1ccc(F)cc1

InChI Key: InChIKey=BRLIGCWAKDRBBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM205965 (US9255090, 434) Show SMILES CCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C27H26F2N2O4/c1-2-35-25-10-5-18(14-26(32)33)13-22(25)20-8-9-24(29)21-11-12-31(16-23(20)21)27(34)30-15-17-3-6-19(28)7-4-17/h3-10,13H,2,11-12,14-16H2,1H3,(H,30,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.0	25
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...				US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2
					More data for this Ligand-Target Pair