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SMILES: CCCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)OC(C)C)ccc3C)c2c1C

InChI Key: InChIKey=NGMYPHYSONFTNF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20669   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM20669
PNG
(propan-2-yl N-(4-methyl-3-{[5-methyl-6-(propylcarb...)
Show SMILES CCCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)OC(C)C)ccc3C)c2c1C
Show InChI InChI=1S/C22H28N6O3/c1-6-9-23-21(29)17-11-28-19(15(17)5)20(24-12-25-28)27-18-10-16(8-7-14(18)4)26-22(30)31-13(2)3/h7-8,10-13H,6,9H2,1-5H3,(H,23,29)(H,26,30)(H,24,25,27)
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MMDB

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Similars
Article
PubMed
n/an/a 680n/an/an/an/an/an/a



Novartis Pharmaceuticals



Assay Description
The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...

J Med Chem 51: 4-16 (2008)


Article DOI: 10.1021/jm7009414
BindingDB Entry DOI: 10.7270/Q23T9FHB
More data for this
Ligand-Target Pair