BDBM20672 4-[(5-acetamido-2-methylphenyl)amino]-5-methyl-N-propylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide::pyrrolo[2,1-f][1,2,4]triazine analogue, 21f

SMILES: CCCNC(=O)c1cn2ncnc(Nc3cc(NC(C)=O)ccc3C)c2c1C

InChI Key: InChIKey=IDBLKBSMZHHLGT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM20672 (4-[(5-acetamido-2-methylphenyl)amino]-5-methyl-N-p...) Show SMILES CCCNC(=O)c1cn2ncnc(Nc3cc(NC(C)=O)ccc3C)c2c1C Show InChI InChI=1S/C20H24N6O2/c1-5-8-21-20(28)16-10-26-18(13(16)3)19(22-11-23-26)25-17-9-15(24-14(4)27)7-6-12(17)2/h6-7,9-11H,5,8H2,1-4H3,(H,21,28)(H,24,27)(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...				J Med Chem 51: 4-16 (2008) Article DOI: 10.1021/jm7009414 BindingDB Entry DOI: 10.7270/Q23T9FHB
					More data for this Ligand-Target Pair