BDBM206778 (S,S)-6::US9492405, (S,S)-6
SMILES: CCCCC[C@H](C)NC[C@@H](O)c1cc(O)cc(O)c1
InChI Key: InChIKey=DFGXCGQPCWUBML-XHDPSFHLSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM206778 ((S,S)-6 | US9492405, (S,S)-6) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.26E+4 | -5.42 | n/a | n/a | n/a | n/a | n/a | 7.8 | 4 |
The United States of America, as represented by the Secretary, Department of Health and Human Services; SRI International US Patent | Assay Description Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988).... | US Patent US9492405 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8CBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM206778 ((S,S)-6 | US9492405, (S,S)-6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.64E+4 | -5.38 | n/a | n/a | n/a | n/a | n/a | 7.8 | 4 |
The United States of America, as represented by the Secretary, Department of Health and Human Services; SRI International US Patent | Assay Description Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988).... | US Patent US9492405 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8CBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM206778 ((S,S)-6 | US9492405, (S,S)-6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 5.62E+4 | n/a | n/a | n/a | 7.7 | n/a |
The United States of America, as represented by the Secretary, Department of Health and Human Services; SRI International US Patent | Assay Description HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer... | US Patent US9492405 (2016) BindingDB Entry DOI: 10.7270/Q2CJ8CBM | |||||||||||
More data for this Ligand-Target Pair |