BDBM207019 US9233965, 106

SMILES: CC(NC(=O)N1CCn2c(C1)c(C(N)=O)c(c2C#N)-c1cccc(F)c1)C(F)(F)F

InChI Key: InChIKey=WAHOLHPDKFONQA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM207019 (US9233965, 106) Show SMILES CC(NC(=O)N1CCn2c(C1)c(C(N)=O)c(c2C#N)-c1cccc(F)c1)C(F)(F)F Show InChI InChI=1S/C19H17F4N5O2/c1-10(19(21,22)23)26-18(30)27-5-6-28-13(8-24)15(11-3-2-4-12(20)7-11)16(17(25)29)14(28)9-27/h2-4,7,10H,5-6,9H2,1H3,(H2,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
SANOFI US Patent					Assay Description "U"-bottomed Falcon plates are prepared by placing 5 uL of solutions of the compounds according to the invention at concentrations of 10, 1, 0.1, 0.0...				US Patent US9233965 (2016) BindingDB Entry DOI: 10.7270/Q2086443
					More data for this Ligand-Target Pair