BDBM207108 US9260439, 85::US9260439, 92

SMILES: CNS(=O)(=O)N1CC[C@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C

InChI Key: InChIKey=HGYSTEDWHIMDRW-DZGCQCFKSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 207108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207108 (US9260439, 85 | US9260439, 92) Show SMILES CNS(=O)(=O)N1CC[C@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C20H29N9O3S/c1-13-12-32-8-7-28(13)20-25-17(14-9-23-19(21)24-10-14)16-4-6-29(18(16)26-20)15-3-5-27(11-15)33(30,31)22-2/h9-10,13,15,22H,3-8,11-12H2,1-2H3,(H2,21,23,24)/t13-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.239	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM207108 (US9260439, 85 | US9260439, 92) Show SMILES CNS(=O)(=O)N1CC[C@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C20H29N9O3S/c1-13-12-32-8-7-28(13)20-25-17(14-9-23-19(21)24-10-14)16-4-6-29(18(16)26-20)15-3-5-27(11-15)33(30,31)22-2/h9-10,13,15,22H,3-8,11-12H2,1-2H3,(H2,21,23,24)/t13-,15+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.283	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207108 (US9260439, 85 | US9260439, 92) Show SMILES CNS(=O)(=O)N1CC[C@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C20H29N9O3S/c1-13-12-32-8-7-28(13)20-25-17(14-9-23-19(21)24-10-14)16-4-6-29(18(16)26-20)15-3-5-27(11-15)33(30,31)22-2/h9-10,13,15,22H,3-8,11-12H2,1-2H3,(H2,21,23,24)/t13-,15+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM207108 (US9260439, 85 | US9260439, 92) Show SMILES CNS(=O)(=O)N1CC[C@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C20H29N9O3S/c1-13-12-32-8-7-28(13)20-25-17(14-9-23-19(21)24-10-14)16-4-6-29(18(16)26-20)15-3-5-27(11-15)33(30,31)22-2/h9-10,13,15,22H,3-8,11-12H2,1-2H3,(H2,21,23,24)/t13-,15+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.475	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair