BDBM207155 US9260439, 132

SMILES: CC(C)(C)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=MZTWSKDDCXKAJS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207155 (US9260439, 132) Show SMILES CC(C)(C)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1 Show InChI InChI=1S/C18H25N7O/c1-18(2,3)25-5-4-13-14(12-10-20-16(19)21-11-12)22-17(23-15(13)25)24-6-8-26-9-7-24/h10-11H,4-9H2,1-3H3,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM207155 (US9260439, 132) Show SMILES CC(C)(C)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1 Show InChI InChI=1S/C18H25N7O/c1-18(2,3)25-5-4-13-14(12-10-20-16(19)21-11-12)22-17(23-15(13)25)24-6-8-26-9-7-24/h10-11H,4-9H2,1-3H3,(H2,19,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair