BDBM207159 US9260439, 136

SMILES: C[C@H]1COCCN1c1nc2N(CCc2c(n1)-c1cnc(N)nc1)[C@@H]1CCN(C1)C(=O)OC1CN(C1)C(C)=O

InChI Key: InChIKey=JXRHBBVTWLZLBA-MAUKXSAKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207159 (US9260439, 136) Show SMILES C[C@H]1COCCN1c1nc2N(CCc2c(n1)-c1cnc(N)nc1)[C@@H]1CCN(C1)C(=O)OC1CN(C1)C(C)=O |r| Show InChI InChI=1S/C25H33N9O4/c1-15-14-37-8-7-33(15)24-29-21(17-9-27-23(26)28-10-17)20-4-6-34(22(20)30-24)18-3-5-31(11-18)25(36)38-19-12-32(13-19)16(2)35/h9-10,15,18-19H,3-8,11-14H2,1-2H3,(H2,26,27,28)/t15-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM207159 (US9260439, 136) Show SMILES C[C@H]1COCCN1c1nc2N(CCc2c(n1)-c1cnc(N)nc1)[C@@H]1CCN(C1)C(=O)OC1CN(C1)C(C)=O |r| Show InChI InChI=1S/C25H33N9O4/c1-15-14-37-8-7-33(15)24-29-21(17-9-27-23(26)28-10-17)20-4-6-34(22(20)30-24)18-3-5-31(11-18)25(36)38-19-12-32(13-19)16(2)35/h9-10,15,18-19H,3-8,11-14H2,1-2H3,(H2,26,27,28)/t15-,18+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair