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BDBM207408 US9260439, 292

SMILES: C[C@@]1(CCN(C1)C(=O)[C@H](N)CF)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=PAJZZYFRFDQXOY-ZHRRBRCNSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207408   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
p110alpha-iSH2 p85alpha Complex


(Homo sapiens (Human))		BDBM207408
PNG
(US9260439, 292)
Show SMILES C[C@@]1(CCN(C1)C(=O)[C@H](N)CF)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1
Show InChI InChI=1S/C22H30FN9O2/c1-22(3-5-31(13-22)19(33)16(24)10-23)32-4-2-15-17(14-11-26-20(25)27-12-14)28-21(29-18(15)32)30-6-8-34-9-7-30/h11-12,16H,2-10,13,24H2,1H3,(H2,25,26,27)/t16-,22+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
<0.0180n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...

US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair