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BDBM207485 US9260439, 369

SMILES: CC1(O)CN(C1)C(=O)N1CC[C@@](C)(C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=RSEWPTYRUFUTKR-QHCPKHFHSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
p110alpha-iSH2 p85alpha Complex


(Homo sapiens (Human))		BDBM207485
PNG
(US9260439, 369)
Show SMILES CC1(O)CN(C1)C(=O)N1CC[C@@](C)(C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1
Show InChI InChI=1S/C24H33N9O3/c1-23(4-6-31(13-23)22(34)32-14-24(2,35)15-32)33-5-3-17-18(16-11-26-20(25)27-12-16)28-21(29-19(17)33)30-7-9-36-10-8-30/h11-12,35H,3-10,13-15H2,1-2H3,(H2,25,26,27)/t23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
<0.0180n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...

US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair