null

SMILES: N[C@@H](Cc1ccccc1)C(=O)N1Cc2[nH]c3cccc4c3c2c(C1)n[nH]c4=O

InChI Key: InChIKey=FTDIDYHPPUJDGJ-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 207619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM207619 (US10501467, Example 64 | US9260440, 64 | US9617273...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1Cc2[nH]c3cccc4c3c2c(C1)n[nH]c4=O |r| Show InChI InChI=1S/C21H17N5O2/c22-14(9-12-5-2-1-3-6-12)21(28)26-10-16-19-17(11-26)24-25-20(27)13-7-4-8-15(23-16)18(13)19/h1-8,14H,9-11,22H2/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	8.0	n/a
BeiGene, Ltd. US Patent					Assay Description PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...				US Patent US9260440 (2016) BindingDB Entry DOI: 10.7270/Q2QV3KBD
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM207619 (US10501467, Example 64 | US9260440, 64 | US9617273...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1Cc2[nH]c3cccc4c3c2c(C1)n[nH]c4=O |r| Show InChI InChI=1S/C21H17N5O2/c22-14(9-12-5-2-1-3-6-12)21(28)26-10-16-19-17(11-26)24-25-20(27)13-7-4-8-15(23-16)18(13)19/h1-8,14H,9-11,22H2/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...				US Patent US10501467 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FS5
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM207619 (US10501467, Example 64 | US9260440, 64 | US9617273...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N1Cc2[nH]c3cccc4c3c2c(C1)n[nH]c4=O |r| Show InChI InChI=1S/C21H17N5O2/c22-14(9-12-5-2-1-3-6-12)21(28)26-10-16-19-17(11-26)24-25-20(27)13-7-4-8-15(23-16)18(13)19/h1-8,14H,9-11,22H2/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
BeiGene, Ltd. US Patent					Assay Description PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...				US Patent US9617273 (2017) BindingDB Entry DOI: 10.7270/Q2CN75ZV
					More data for this Ligand-Target Pair