BDBM208680 US9266876, 147

SMILES: C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1sc(nc1-c1nc2cc(Cl)ccc2[nH]1)C(F)(F)F

InChI Key: InChIKey=GKGKGFDQVXICKG-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CXCR3A / G protein (Galpha(16)) (Homo sapiens (Human))	BDBM208680 (US9266876, 147) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1sc(nc1-c1nc2cc(Cl)ccc2[nH]1)C(F)(F)F Show InChI InChI=1S/C24H20ClF3N8OS/c1-13-10-34(7-8-36(13)18(37)11-35-12-30-16-3-2-6-29-21(16)35)22-19(33-23(38-22)24(26,27)28)20-31-15-5-4-14(25)9-17(15)32-20/h2-6,9,12-13H,7-8,10-11H2,1H3,(H,31,32)/t13-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				US Patent US9266876 (2016) BindingDB Entry DOI: 10.7270/Q2DB80NB
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